The mortality rate of Invasive Aspergillosis is between 60 and 100% without timely treatment, thus reliable determination of galactomannan antigen may be essential.

• Sandwich ELISA as diagnostic gold standard
• Validated for serum and BAL samples
• Significantly simplified sample preparation
• Only 150 µL sample volume required
• Limit of detection: 0.67 ng/ml (serum); 1.09 ng/ml (BAL)
• Automation possible from sample to final result

Detection of galactomannan antigens as indicators of Aspergillus spec. infection using anti-galactomannan monoclonal antibodies and HRP-mediated color reaction. Established diagnostic procedure, significantly simplified sample preparation.